Search results for "Medical Overuse"

showing 5 items of 5 documents

Avoidance of Overtreatment of Rectal Cancer by Selective Chemoradiotherapy: Results of the Optimized Surgery and MRI-Based Multimodal Therapy Trial.

2020

Background Neoadjuvant chemoradiotherapy (nCRT) in patients with rectal cancer carries a high risk of adverse effects. The aim of this study was to examine the selective application of nCRT based on patient risk profile, as determined by MRI, to find the optimal range between undertreatment and overtreatment. Study Design In this prospective multicenter observational study, nCRT before total mesorectal excision (TME) was indicated in high-risk patients with involved or threatened mesorectal fascia (≤1 mm), or cT4 or cT3 carcinomas of the lower rectal third. All other patients received primary surgery. Results Of the 1,093 patients, 878 (80.3%) were treated according to the protocol, 526 pat…

AdultMalemedicine.medical_specialtyColorectal cancermedicine.medical_treatmentMedical OveruseDisease-Free Survival03 medical and health sciences0302 clinical medicinemedicineHumansProspective StudiesStage (cooking)Adverse effectPathologicalAgedNeoplasm StagingAged 80 and overProctectomybusiness.industryRectal NeoplasmsCarcinomaRectumMultimodal therapyChemoradiotherapy AdjuvantMiddle Agedmedicine.diseaseTotal mesorectal excisionMagnetic Resonance ImagingNeoadjuvant TherapySurgeryRadiation therapy030220 oncology & carcinogenesisCase-Control StudiesPractice Guidelines as Topic030211 gastroenterology & hepatologySurgeryFemaleNeoplasm Recurrence LocalbusinessChemoradiotherapyFollow-Up StudiesJournal of the American College of Surgeons
researchProduct

Overdiagnosis and overimaging: an ethical issue for radiological protection

2019

Aims and objectives: This study aimed to analyse the key factors that influence the overimaging using X-ray such as self-referral, defensive medicine and duplicate imaging studies and to emphasize the ethical problem that derives from it. Materials and methods: In this study, we focused on the more frequent sources of overdiagnosis such as the total-body CT, proposed in the form of screening in both public and private sector, the choice of the most sensitive test for each pathology such as pulmonary embolism, ultrasound investigations mostly of the thyroid and of the prostate and MR examinations, especially of the musculoskeletal system. Results: The direct follow of overdiagnosis and overi…

Defensive MedicineMalemedicine.medical_specialtyThyroid GlandContrast MediaMedical OveruseoverdiagnosisSensitivity and Specificity030218 nuclear medicine & medical imagingDefensive medicine03 medical and health sciences0302 clinical medicinemedicineHumansWhole Body ImagingRadiology Nuclear Medicine and imagingBioethical IssuesEthicOverdiagnosisIntensive care medicineNeuroradiologyRadiation protectionethics; overdiagnosis; overimaging; radiation protectionmedicine.diagnostic_testOverimagingbusiness.industryProstatePhysician Self-ReferralInterventional radiologyGeneral MedicineRadiation ExposurePrivate sectorethicsMagnetic Resonance ImagingTest (assessment)Key factorsOverdiagnosi030220 oncology & carcinogenesisRadiological weaponRadiologybusinessLa radiologia medica
researchProduct

Mesothelial cyst of the round ligament of the uterus A case report of a rare condition

2021

Le cisti mesoteliali del legamento rotondo sono una rara causa di tumefazione inguinale nelle donne, la loro eziopatogenesi rimare poco chiara e i casi riportati in letteratura sono scarsi. Inoltre, quest’ultime sono raramente prese in considerazione nella diagnosi differenziale delle tumefazioni della regione inguinale nelle pazienti di sesso femminile, ragion per cui sono spesso identificate solo in corso di esplorazione chirurgica e correttamente diagnosticate solo dopo esame istopatologico. Una donna di 57 anni (BMI 37 kg / m2) si è presentato nel nostro dipartimento con una massa inguinale sinistra, con storia di 2 mesi, che causava disagio locale e peggioramento progressivo del dolore…

Diagnosis DifferentialCystsUterusHumansFemaleHernia InguinalMedical OveruseRound Ligament of UterusHernia FemoralMesothelial cyst Preoperative diagnosis Uterus
researchProduct

The impact of overdiagnosis on thyroid cancer epidemic in Italy,1998-2012

2018

Aims: In Italy, incidence rates of thyroid cancer (TC) are among the highest world- wide with substantial intracountry heterogeneity. The aim of the study was to examine time trends of TC incidence in Italy and to estimate the proportion of TC cases potentially attribut- able to overdiagnosis. Methods: Data on TC cases reported to Italian cancer registries during 1998e2012 aged <85 years were included. Age-standardised incidence rates (ASR) were computed by sex, period, and histology. TC overdiagnosis was estimated by sex, period, age, and Italian region. Results: In Italy between 1998e2002 and 2008e2012, TC ASR increased of 74% in women (from 16.2 to 28.2/100,000) and of 90% in men (fro…

MaleCancer ResearchMedical OveruseSettore MED/42 - Igiene Generale E Applicata0302 clinical medicineRegistriesYoung adultOverdiagnosisChildThyroid cancerAged 80 and overeducation.field_of_studyIncidence (epidemiology)IncidenceThyroidTime trendsMiddle Agedmedicine.anatomical_structureOncologyItaly030220 oncology & carcinogenesisChild PreschoolFemalemedicine.symptomAdultIncidence; Italy; Mortality; Overdiagnosis; Thyroid cancer; Time trends; Oncology; Cancer ResearchOverdiagnosisAdolescentPopulationSocio-culturale030209 endocrinology & metabolismAsymptomaticThyroid cancer03 medical and health sciencesYoung AdultmedicineHumansThyroid NeoplasmsMortalityeducationEpidemicsAgedbusiness.industryInfant NewbornCancerInfantmedicine.diseaseOverdiagnosibusinessDemography
researchProduct

Breast cancer screening programmes: Challenging the coexistence with opportunistic mammography.

2014

Abstract Objective This study investigated predictive factors of women's participation in organized mammography screening (OrgMS) and/or opportunistic mammography screening (OppMS) when the two screening modes coexist. Methods Questionnaires were sent to 6,000 women aged 51–74 years old invited to attend an OrgMS session between 2010 and 2011 in France. Data collected concerned the women's healthcare behaviour and their socioeconomic characteristics. Women without a personal or family history of breast cancer that could explain their participation in OppMS were retained in the generalized logits analysis. Results The data of 1,202 women were analysed. Of these, 555 (46.2%) had attended OrgM…

medicine.medical_specialtyBreast NeoplasmsMedical OveruseBreast cancer screeningBreast cancer5. Gender equalitySurveys and QuestionnairesCancer screeningHealth careHumansMass ScreeningMedicineMammographyFamily historySocioeconomic statusEarly Detection of CancerComputingMilieux_MISCELLANEOUSAgedmedicine.diagnostic_testbusiness.industry[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologieGeneral MedicineMiddle Agedmedicine.disease3. Good healthSocioeconomic Factors[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieFamily medicinePhysical therapyFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieFranceMammography screeningPatient ParticipationbusinessMammography
researchProduct